To analyze challenging analytes, your GC or GC/MS system must have the sensitivity to deliver reproducible qualitative and quantitative results.
GC columns based on a 100 percent polyethylene glycol (PEG) stationary phase can be used for a wide variety of applications. These include industrial chemicals, pharmaceutical raw materials, alcoholic beverages, flavors, and fragrances.
Despite their wide range of applications, the columns, also known as WAX columns, typically have lower maximum operating temperatures than nonpolar columns. Heating a standard WAX column above its maximum operating temperature of 260 °C (to ensure that heavy compounds elute from the column to prevent ghost peaks, for example, or to increase reproducibility), damages the stationary phase.
Exceeding the maximum temperature leads to issues such as decreased thermal stability, which reduces the potential range of applications that the columns could be used for. Other problems include elevated column bleed and shorter column lifetime.
Extending heat limits for breakthrough results
Agilent has the ideal solution: its innovative Agilent J&W DB-HeavyWAX GC columns have an improved stationary phase that enables an extended temperature limit of up to 280 °C isothermal and 290 °C programmed. The columns also have improved thermal stability, increasing injection-to-injection reproducibility, and therefore offer a wider application range.
- Higher maximum temperature allows for shorter run times, plus a lower cost per test.
- Thermal stability and increased column life, even when used at maximum operating temperatures.
- Reproducible retention times from injection to injection.
- Minimal risk of carryover, decreasing the risk of ghost peaks.
- Ability to analyze higher molecular weight compounds, extending the analyte range.
Excellent thermal stability
Agilent scientists compared a commercially available WAX column (Figure 1) to Agilent J&W DB-HeavyWAX (Figure 2) using 100 ppm standard of BTEX over a period of 100 hours operating at 280°C. The graphs below show the results.
Traditional WAX GC columns exhibit high bleed above their maximum temperature limits. Figure 3 shows that after 100 hours at high temperatures (280 °C), bleed of the Agilent J&W DB-HeavyWAX column is still less than 10 pA. Meanwhile, two commercially available WAX columns have column bleed levels between 50 and 60 pA.
The Agilent advantage
The Agilent J&W DB-HeavyWAX column provides an increased maximum temperature range. It guarantees thermal stability at high temperatures for increased analyte range and better column-to-column reproducibility. Run times can be up to 20% quicker, and there is low bleed, even at the highest temperatures.
To find out more about this new product, visit www.agilent.com/chem/db-heavywax.
To download the poster and application note, go to www.agilent.com/chem/db-heavywaxinfo.